منابع مشابه
Characterization of Macrophage Phenotypes in Three Murine Models of House-Dust-Mite-Induced Asthma
In asthma, an important role for innate immunity is increasingly being recognized. Key innate immune cells in the lungs are macrophages. Depending on the signals they receive, macrophages can at least have an M1, M2, or M2-like phenotype. It is unknown how these macrophage phenotypes behave with regard to (the severity of) asthma. We have quantified the phenotypes in three models of house dust ...
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Objective(s): Inflammation is an immune response toward injuries. Although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, Alzheimer’s and various cancer. Indonesian cassia (Cinnamomum burmanni C. Nees & T. Ness) known to contain coumarin, is widely used for alternative medicine es...
متن کاملPreferential Inhibition of Murine Macrophage
Murine bone marrow progenitor cells that gave rise to macrophage colonies in semisolid agar were found to be more sensitive to prostaglandins of the E series (PGE) than were precursor cells of granulocytes and megakaryocytes. Macrophage colonies themselves had different sensitivities to the molecule. Precursor cells of macrophages that formed colonies in the presence of a stimulating activity f...
متن کاملMacrophage Chemoattractant in Murine Wound Repair
At sites of injury, macrophages secrete growth factors and proteins that promote tissue repair. While this central role of the macrophage has been well studied, the specific stimuli that recruit macrophages into sites of injury are not well understood. This study examines the role of macrophage inflammatory protein 1 a (MIP-1 a ), a C–C chemokine with monocyte chemoattractant capability, in exc...
متن کاملtumor associated macrophage: a review on the phenotypes, traits and functions
the macrophages role within the tumor microenvironment has amended by a variety of factors, thus serves a vital role in tissue morphogenesis. the role of macrophages in health and disease differs enormously as the macrophage has shown dual functions. macrophage has a basic role in antigen presentation serving as the first line of defense in diseases. however the presence of cytokines and growth...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2013
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.27.1_supplement.lb487